Crohn’s disease is chronic inflammatory disease of the gastrointestinal tract. It presents with persistent diarrhea, abdominal pain and cramping, loss of appetite, weight loss, and fever. In extreme cases, blockages, ulcers, and fistula can occur.
RISKS that increase chance of Crohn’s disease:
Risk of Crohn’s increases by 50% for those on the birth control pill.
A dysbiotic gut, namely an overgrowth of Ruminococcus gnavus .
Genetics: NOD2, ATG16L1, IL23R, and IRGM
Immune system problems.
Environmental factors also contribute to the onset of disease.
If you have Crohn’s disease, a comprehensive stool analysis can provide snapshot of what microbes are in your gut, the extent of inflammation, and presence of any blood. Balance the microbiome to help calm the flares associated with this inflammatory bowel disease.
Genetic analysis determines how your blueprint may play into to your condition. There are over 200 variations that contribute to how your immune system interacts with your gut microbes. Interesting as this is, it is only a small part compared to environmental and lifestyle factors.
 Kim, J. W., Kwok, S. K., Choe, J. Y., & Park, S. H. (2019). Recent Advances in Our Understanding of the Link between the Intestinal Microbiota and Systemic Lupus Erythematosus. International journal of molecular sciences, 20(19), 4871. https://doi.org/10.3390/ijms20194871